There are several neurological conditions associated with inflammation in the brain and nervous system, including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), and diabetic retinopathy. In each of these conditions there is evidence of increased inflammatory mediators, including cytokines, leading to the death of nerve cells and the eventual loss of functional activity.

Due to the prevalence, morbidity, and mortality associated with neuro-inflammatory diseases, they represent a significant medical, social, and financial burden. It is estimated that these neurological conditions affect more than five million people in North America and generate costs of care that exceed US$75 billion annually.

For additional information, please visit the following Web sites:

• ALS Association
• ALS Society of Canada
• Alzheimer's Association
• Alzheimer Society of Canada
• American Parkinson Disease Association, Inc.
• Electronic Quality Information for Patients: Parkinson's Disease
• European Parkinson's Disease Association
• National Institute of Neurological Disorders and Stroke: Alzheimer's Disease
• National Institute of Neurological Disorders and Stroke: Amyotrophic Lateral Sclerosis
• National Institute of Neurological Disorders and Stroke: Parkinson's Disease
• National Parkinson's Foundation
• Parkinson's Disease Foundation
• Parkinson's Society Canada
• World Federation of Neurology: Amyotrophic Lateral Sclerosis